Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials

BACKGROUND: The ProCESS, ARISE, and ProMISe trials have failed to show that early goal-directed therapy (EGDT) reduces mortality in patients with severe sepsis and septic shock. Although lactate-guided therapy (LGT) has been shown to result in significantly lower mortality, its use remains controver...

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Detalles Bibliográficos
Autores principales: Ding, Xian-Fei, Yang, Zi-Yue, Xu, Zhen-Tao, Li, Li-Feng, Yuan, Bo, Guo, Li-Na, Wang, Le-Xin, Zhu, Xi, Sun, Tong-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264603/
https://www.ncbi.nlm.nih.gov/pubmed/30486885
http://dx.doi.org/10.1186/s12967-018-1700-7

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