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An Electrochemical Synthesis of Functionalized Arylpyrimidines from 4-Amino-6-Chloropyrimidines and Aryl Halides

A range of novel 4-amino-6-arylpyrimidines has been prepared under mild conditions by an electrochemical reductive cross-coupling between 4-amino-6-chloro-pyrimidines and functionalized aryl halides. The process, which employs a sacrificial iron anode in conjunction with a nickel(II) catalyst, allow...

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Detalles Bibliográficos
Autores principales: Sengmany, Stéphane, Gall, Erwan Le, Léonel, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264652/
https://www.ncbi.nlm.nih.gov/pubmed/21716176
http://dx.doi.org/10.3390/molecules16075550