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The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume)
Kacip Fatimah (Labisia pumila Blume), one of the most famous and widely used herbs, especially in Southeast Asia, is found to have interesting bioactive compounds and displays health promoting properties. In this study, the antioxidant activities of the methanol extracts of leaves, stems and roots o...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264717/ https://www.ncbi.nlm.nih.gov/pubmed/21716173 http://dx.doi.org/10.3390/molecules16075514 |
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author | Ibrahim, Mohd Hafiz Jaafar, Hawa Z.E. |
author_facet | Ibrahim, Mohd Hafiz Jaafar, Hawa Z.E. |
author_sort | Ibrahim, Mohd Hafiz |
collection | PubMed |
description | Kacip Fatimah (Labisia pumila Blume), one of the most famous and widely used herbs, especially in Southeast Asia, is found to have interesting bioactive compounds and displays health promoting properties. In this study, the antioxidant activities of the methanol extracts of leaves, stems and roots of three varieties of L. pumila (var. alata, pumila and lanceolata) were evaluated in an effort to compare and validate the medicinal potential of this indigenous Malaysian herb species. The antioxidant activity determined by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, as well as the total amount of phenolics and flavonoids were the highest in the leaves, followed by the stems and roots in all the varieties. A similar trend was displayed by the ferric reducing antioxidant potential (FRAP) activity, suggesting that the L. pumila varieties possess high foliar antioxidant properties. At low FRAP activity concentrations, the values of the leaves’ inhibition activity in the three varieties were significantly higher than those of the stems and roots, with var. alata exhibiting higher antioxidant activities and total contents of phenolics and flavonoids compared to the varieties pumila and lanceolata. The high production of secondary metabolites and antioxidant activities in var. alata were firmly related to low nitrogen content and high C/N ratio in plant parts. The study also demonstrated a positive correlation between secondary metabolite content and antioxidant activities, and revealed that the consumption of L. pumila could exert several beneficial effects by virtue of its antioxidant activity. |
format | Online Article Text |
id | pubmed-6264717 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62647172018-12-10 The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) Ibrahim, Mohd Hafiz Jaafar, Hawa Z.E. Molecules Article Kacip Fatimah (Labisia pumila Blume), one of the most famous and widely used herbs, especially in Southeast Asia, is found to have interesting bioactive compounds and displays health promoting properties. In this study, the antioxidant activities of the methanol extracts of leaves, stems and roots of three varieties of L. pumila (var. alata, pumila and lanceolata) were evaluated in an effort to compare and validate the medicinal potential of this indigenous Malaysian herb species. The antioxidant activity determined by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, as well as the total amount of phenolics and flavonoids were the highest in the leaves, followed by the stems and roots in all the varieties. A similar trend was displayed by the ferric reducing antioxidant potential (FRAP) activity, suggesting that the L. pumila varieties possess high foliar antioxidant properties. At low FRAP activity concentrations, the values of the leaves’ inhibition activity in the three varieties were significantly higher than those of the stems and roots, with var. alata exhibiting higher antioxidant activities and total contents of phenolics and flavonoids compared to the varieties pumila and lanceolata. The high production of secondary metabolites and antioxidant activities in var. alata were firmly related to low nitrogen content and high C/N ratio in plant parts. The study also demonstrated a positive correlation between secondary metabolite content and antioxidant activities, and revealed that the consumption of L. pumila could exert several beneficial effects by virtue of its antioxidant activity. MDPI 2011-06-29 /pmc/articles/PMC6264717/ /pubmed/21716173 http://dx.doi.org/10.3390/molecules16075514 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Ibrahim, Mohd Hafiz Jaafar, Hawa Z.E. The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title | The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title_full | The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title_fullStr | The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title_full_unstemmed | The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title_short | The Relationship of Nitrogen and C/N Ratio with Secondary Metabolites Levels and Antioxidant Activities in Three Varieties of Malaysian Kacip Fatimah (Labisia pumila Blume) |
title_sort | relationship of nitrogen and c/n ratio with secondary metabolites levels and antioxidant activities in three varieties of malaysian kacip fatimah (labisia pumila blume) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264717/ https://www.ncbi.nlm.nih.gov/pubmed/21716173 http://dx.doi.org/10.3390/molecules16075514 |
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