The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chr...

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Autores principales: Al-Amiery, Ahmed A., Musa, Ahmed Y., Kadhum, Abdul Amir H., Mohamad, Abu Bakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264737/
https://www.ncbi.nlm.nih.gov/pubmed/21832973
http://dx.doi.org/10.3390/molecules16086833
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author Al-Amiery, Ahmed A.
Musa, Ahmed Y.
Kadhum, Abdul Amir H.
Mohamad, Abu Bakar
author_facet Al-Amiery, Ahmed A.
Musa, Ahmed Y.
Kadhum, Abdul Amir H.
Mohamad, Abu Bakar
author_sort Al-Amiery, Ahmed A.
collection PubMed
description New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, (1)H-NMR and (13)C-NMR).
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spelling pubmed-62647372018-12-10 The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds Al-Amiery, Ahmed A. Musa, Ahmed Y. Kadhum, Abdul Amir H. Mohamad, Abu Bakar Molecules Article New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, (1)H-NMR and (13)C-NMR). MDPI 2011-08-10 /pmc/articles/PMC6264737/ /pubmed/21832973 http://dx.doi.org/10.3390/molecules16086833 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Al-Amiery, Ahmed A.
Musa, Ahmed Y.
Kadhum, Abdul Amir H.
Mohamad, Abu Bakar
The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_full The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_fullStr The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_full_unstemmed The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_short The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_sort use of umbelliferone in the synthesis of new heterocyclic compounds
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264737/
https://www.ncbi.nlm.nih.gov/pubmed/21832973
http://dx.doi.org/10.3390/molecules16086833
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