Flavonoids as Vasorelaxant Agents: Synthesis, Biological Evaluation and Quantitative Structure Activities Relationship (QSAR) Studies

A series of 2-(2-diethylamino)-ethoxychalcone and 6-prenyl(or its isomers)-flavanones 10a,b and 11a–g were synthesized and evaluated for their vasorelaxant activities against rat aorta rings pretreated with 1 μM phenylephrine (PE). Several compounds showed potent vasorelaxant activities. Compound 10...

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Detalles Bibliográficos
Autores principales: Dong, Xiaowu, Wang, Yanming, Liu, Tao, Wu, Peng, Gao, Jiadi, Xu, Jianchao, Yang, Bo, Hu, Yongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264760/
https://www.ncbi.nlm.nih.gov/pubmed/21959298
http://dx.doi.org/10.3390/molecules16108257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264760/
https://www.ncbi.nlm.nih.gov/pubmed/21959298
http://dx.doi.org/10.3390/molecules16108257

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