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Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of ADAMTS1 Inhibitors

A disintegrin and metalloprotease with thrombospondin type I motifs-1 (ADAMTS1) plays a crucial role in inflammatory joint diseases and its inhibitors are potential candidates for anti-arthritis drugs. For the purposes of drug discovery, we reported the development and validation of fluorescence res...

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Detalles Bibliográficos
Autores principales: Peng, Jianhao, Gong, Lili, Si, Kun, Bai, Xiaoyu, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264766/
https://www.ncbi.nlm.nih.gov/pubmed/22186957
http://dx.doi.org/10.3390/molecules161210709