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Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of ADAMTS1 Inhibitors
A disintegrin and metalloprotease with thrombospondin type I motifs-1 (ADAMTS1) plays a crucial role in inflammatory joint diseases and its inhibitors are potential candidates for anti-arthritis drugs. For the purposes of drug discovery, we reported the development and validation of fluorescence res...
Autores principales: | Peng, Jianhao, Gong, Lili, Si, Kun, Bai, Xiaoyu, Du, Guanhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264766/ https://www.ncbi.nlm.nih.gov/pubmed/22186957 http://dx.doi.org/10.3390/molecules161210709 |
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