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A Short Synthesis of Bisabolane Sesquiterpenes
A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by add...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264776/ https://www.ncbi.nlm.nih.gov/pubmed/21931286 http://dx.doi.org/10.3390/molecules16098053 |
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author | Du, Zhen-Ting Zheng, Shuai Chen, Gang Lv, Dong |
author_facet | Du, Zhen-Ting Zheng, Shuai Chen, Gang Lv, Dong |
author_sort | Du, Zhen-Ting |
collection | PubMed |
description | A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes. |
format | Online Article Text |
id | pubmed-6264776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-62647762018-12-10 A Short Synthesis of Bisabolane Sesquiterpenes Du, Zhen-Ting Zheng, Shuai Chen, Gang Lv, Dong Molecules Article A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials. The halogen-lithium exchange followed by addition of isoprenylacetone and reduction of the obtained carbinols are the key steps of the synthetic pathway. This synthetic approach provides a new route to the bisabolane sesquiterpenes. MDPI 2011-09-19 /pmc/articles/PMC6264776/ /pubmed/21931286 http://dx.doi.org/10.3390/molecules16098053 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Du, Zhen-Ting Zheng, Shuai Chen, Gang Lv, Dong A Short Synthesis of Bisabolane Sesquiterpenes |
title | A Short Synthesis of Bisabolane Sesquiterpenes |
title_full | A Short Synthesis of Bisabolane Sesquiterpenes |
title_fullStr | A Short Synthesis of Bisabolane Sesquiterpenes |
title_full_unstemmed | A Short Synthesis of Bisabolane Sesquiterpenes |
title_short | A Short Synthesis of Bisabolane Sesquiterpenes |
title_sort | short synthesis of bisabolane sesquiterpenes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264776/ https://www.ncbi.nlm.nih.gov/pubmed/21931286 http://dx.doi.org/10.3390/molecules16098053 |
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