The immunologic constant of rejection classification refines the prognostic value of conventional prognostic signatures in breast cancer

BACKGROUND: The immunologic constant of rejection (ICR) is a broad phenomenon of Th-1 immunity-mediated, tissue-specific destruction. METHODS: We tested the prognostic value of a 20-gene ICR expression signature in 8766 early breast cancers. RESULTS: Thirty-three percent of tumours were ICR1, 29% IC...

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Detalles Bibliográficos
Autores principales: Bertucci, François, Finetti, Pascal, Simeone, Ines, Hendrickx, Wouter, Wang, Ena, Marincola, Francesco M., Viens, Patrice, Mamessier, Emilie, Ceccarelli, Michele, Birnbaum, Daniel, Bedognetti, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265245/
https://www.ncbi.nlm.nih.gov/pubmed/30353048
http://dx.doi.org/10.1038/s41416-018-0309-1

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