Nuclear receptor ERRα and transcription factor ERG form a reciprocal loop in the regulation of TMPRSS2:ERG fusion gene in prostate cancer

The TMPRSS2:ERG (T:E) fusion gene is generally believed to be mainly regulated by the activated androgen receptor (AR) signaling in androgen-dependent prostate cancer. However, its persistent expression in castration-resistant and neuroendocrine prostate cancers implies that other transcription fact...

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Detalles Bibliográficos
Autores principales: Xu, Zhenyu, Wang, Yuliang, Xiao, Zhan Gang, Zou, Chang, Zhang, Xian, Wang, Zhu, Wu, Dinglan, Yu, Shan, Chan, Franky Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265259/
https://www.ncbi.nlm.nih.gov/pubmed/30042415
http://dx.doi.org/10.1038/s41388-018-0409-7

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