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High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer

Most triple negative breast cancers (TNBCs) are aggressively metastatic with a high degree of intra-tumoral heterogeneity (ITH), but how ITH contributes to metastasis is unclear. Here, clonal dynamics during metastasis were studied in vivo using two patient-derived xenograft (PDX) models established...

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Detalles Bibliográficos
Autores principales:	Echeverria, Gloria V., Powell, Emily, Seth, Sahil, Ge, Zhongqi, Carugo, Alessandro, Bristow, Christopher, Peoples, Michael, Robinson, Frederick, Qiu, Huan, Shao, Jiansu, Jeter-Jones, Sabrina L., Zhang, Xiaomei, Ramamoorthy, Vandhana, Cai, Shirong, Wu, Wenhui, Draetta, Giulio, Moulder, Stacy L., Symmans, William F., Chang, Jeffrey T., Heffernan, Timothy P., Piwnica-Worms, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265294/ https://www.ncbi.nlm.nih.gov/pubmed/30498242 http://dx.doi.org/10.1038/s41467-018-07406-4

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