Cargando…

Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b

BACKGROUND: Recent pre-clinical studies indicate that activated progesterone receptor (PR) (particularly the PR-B isoform) binds to oestrogen receptor-α (ER) and reprogrammes transcription toward better breast cancer outcomes. We investigated whether ER and PR-B interactions were present in breast t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Snell, Cameron E., Gough, Madeline, Liu, Cheng, Middleton, Kathryn, Pyke, Christopher, Shannon, Catherine, Woodward, Natasha, Hickey, Theresa E., Armes, Jane E., Tilley, Wayne D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265321/ https://www.ncbi.nlm.nih.gov/pubmed/30410061 http://dx.doi.org/10.1038/s41416-018-0331-3

Ejemplares similares

The role of oestrogen and progesterone receptors in gigantomastia
por: Kasielska-Trojan, Anna, et al.
Publicado: (2019)

Oestrogen and progesterone receptor distribution in the cancerous breast.
por: Panahy, C., et al.
Publicado: (1987)

The role of oestrogen and progesterone receptors in breast cancer – immunohistochemical evaluation of oestrogen and progesterone receptor expression in invasive breast cancer in women
por: Badowska-Kozakiewicz, Anna M., et al.
Publicado: (2015)

Oestrogen and progesterone receptors and disease-free interval in primary breast cancer.
por: Alanko, A., et al.
Publicado: (1984)

Oestrogen receptor negative-progesterone receptor positive phenotype in 1,211 breast tumours.
por: Pichon, M. F., et al.
Publicado: (1992)

Expression of oestrogen receptor-β in oestrogen receptor-α negative human breast tumours
por: Skliris, G P, et al.
Publicado: (2006)

Oestrogen increases S-phase fraction and oestrogen and progesterone receptors in human cervical cancer in vivo.
por: Bhattacharya, D., et al.
Publicado: (1997)

Risk factors for breast cancer in young women by oestrogen receptor and progesterone receptor status
por: McCredie, M R E, et al.
Publicado: (2003)

The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer
por: Davey, M G, et al.
Publicado: (2021)

Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus
por: Lee, Shi Hao, et al.
Publicado: (2022)

Alcohol consumption and breast cancer oestrogen and progesterone receptor status
por: Enger, S M, et al.
Publicado: (1999)

Intrathoracic myolipoma from parietal pleura with oestrogen and progesterone receptor
por: Teh, Jyh Shinn, et al.
Publicado: (2021)

Oestrogen receptor isoforms, their distribution and relation to progesterone receptor levels in breast cancer samples.
por: Baker, V. A., et al.
Publicado: (1992)

Oestrogen and progesterone cytosolic receptors in clinically inflammatory tumours of the human breast.
por: Delarue, J. C., et al.
Publicado: (1981)

Expression of oestrogen and progesterone receptors in low-grade endometrial stromal sarcomas
por: Reich, O, et al.
Publicado: (2000)

The effect of oestrogen and progesterone receptors on recurrence and survival in patients with carcinoma of the breast.
por: Howat, J. M., et al.
Publicado: (1985)

Renewed interest in the progesterone receptor in breast cancer
por: Lim, Elgene, et al.
Publicado: (2016)

Author Correction: Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus
por: Lee, Shi Hao, et al.
Publicado: (2023)

Progesterone receptors – animal models and cell signaling in breast cancer: The role of oestrogen and progesterone receptors in human mammary development and tumorigenesis
por: Anderson, Elizabeth
Publicado: (2002)

MicroRNA signatures predict oestrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
por: Lowery, Aoife J, et al.
Publicado: (2009)

Is oestrogen receptor-negative/progesterone receptor-positive (ER−/PR+) a real pathological entity?
por: Onitilo, Adedayo A, et al.
Publicado: (2021)

Inter-site variation of oestrogen receptors in human breast cancers.
por: Tilley, W. D., et al.
Publicado: (1978)

Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer
por: Singhal, Hari, et al.
Publicado: (2016)

Expression of oestrogen and progesterone receptors in gastric cancer: a flow cytometric study
por: Karat, D, et al.
Publicado: (1999)

Genetic Factors of Idiopathic Gigantomastia: Clinical Implications of Aromatase and Progesterone Receptor Polymorphisms
por: Kasielska-Trojan, Anna, et al.
Publicado: (2022)

Relationship between the expression of oestrogen receptor and progesterone receptor and (18)F-FDG uptake in endometrial cancer
por: Wu, Chunhua, et al.
Publicado: (2020)

The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer
por: Xu, Wei, et al.
Publicado: (2020)

Progesterone receptor modulates estrogen receptor-α action in breast cancer
por: Mohammed, Hisham, et al.
Publicado: (2015)

Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry
por: Work, M E, et al.
Publicado: (2014)

Characterization of Aromatase Expression in the Adult Male and Female Mouse Brain. I. Coexistence with Oestrogen Receptors α and β, and Androgen Receptors
por: Stanić, Davor, et al.
Publicado: (2014)

Oestrogens and oestrogen receptors in prostate cancer
por: Kowalska, Karolina, et al.
Publicado: (2016)

The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer : Erratum
por: Xu, Wei, et al.
Publicado: (2021)

The association of cytosol oestrogen and progesterone receptors with histological features of breast cancer and early recurrence of disease.
por: Howat, J. M., et al.
Publicado: (1983)

Evaluation of Expression of the PTEN Gene, Oestrogen and Progesterone Receptors as Diagnostic and Predictive Factors in Endometrial Cancer
por: Samulak, Dariusz, et al.
Publicado: (2013)

Combined treatment with 4-hydroxyandrostenedione and aminoglutethimide: effects on aromatase inhibition and oestrogen suppression.
por: MacNeill, F. A., et al.
Publicado: (1994)

Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer
por: Dwyer, Amy R., et al.
Publicado: (2020)

Effect of tamoxifen on Ki67 labelling index in human breast tumours and its relationship to oestrogen and progesterone receptor status.
por: Clarke, R. B., et al.
Publicado: (1993)

Epidermal growth factor, oestrogen and progesterone receptor expression in primary ovarian cancer: correlation with clinical outcome and response to chemotherapy.
por: Scambia, G., et al.
Publicado: (1995)

Oestrogen receptor-negative/progesterone receptor-positive phenotype of invasive breast carcinoma in Japan: re-evaluated using immunohistochemical staining
por: Kuroda, Hajime, et al.
Publicado: (2018)

Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone.
por: Clarke, R. B., et al.
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_r2o45k9bmhfq1j1u4f9unf4c93