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Improved relapse-free survival on aromatase inhibitors in breast cancer is associated with interaction between oestrogen receptor-α and progesterone receptor-b

BACKGROUND: Recent pre-clinical studies indicate that activated progesterone receptor (PR) (particularly the PR-B isoform) binds to oestrogen receptor-α (ER) and reprogrammes transcription toward better breast cancer outcomes. We investigated whether ER and PR-B interactions were present in breast t...

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Detalles Bibliográficos
Autores principales:	Snell, Cameron E., Gough, Madeline, Liu, Cheng, Middleton, Kathryn, Pyke, Christopher, Shannon, Catherine, Woodward, Natasha, Hickey, Theresa E., Armes, Jane E., Tilley, Wayne D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265321/ https://www.ncbi.nlm.nih.gov/pubmed/30410061 http://dx.doi.org/10.1038/s41416-018-0331-3

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