Characterization and in vitro data of antibody drug conjugates (ADCs) derived from heterotrifunctional linker designed for the site-specific preparation of dual ADCs

Experimental procedures and (1)H and (13)C NMR of the heterotrifunctional linker used for preparation of dual drug conjugates and PBD payload are included. Procedure for carrying preparation of antibody linker conjugate via thiol maleimide conjugation and antibody drug conjugates (ADCs) using copper...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Kinneer, Krista, Masterson, Luke, Ezeadi, Ebele, Howard, Philip, Wu, Herren, Gao, Changshou, Dimasi, Nazzareno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265423/
https://www.ncbi.nlm.nih.gov/pubmed/30533469
http://dx.doi.org/10.1016/j.dib.2018.11.005

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