The APT complex is involved in non-coding RNA transcription and is distinct from CPF

The 3′-ends of eukaryotic pre-mRNAs are processed in the nucleus by a large multiprotein complex, the cleavage and polyadenylation factor (CPF). CPF cleaves RNA, adds a poly(A) tail and signals transcription termination. CPF harbors four enzymatic activities essential for these processes, but how th...

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Detalles Bibliográficos
Autores principales: Lidschreiber, Michael, Easter, Ashley D, Battaglia, Sofia, Rodríguez-Molina, Juan B, Casañal, Ana, Carminati, Manuel, Baejen, Carlo, Grzechnik, Pawel, Maier, Kerstin C, Cramer, Patrick, Passmore, Lori A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265451/
https://www.ncbi.nlm.nih.gov/pubmed/30247719
http://dx.doi.org/10.1093/nar/gky845

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