Cargando…

Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway

Human apurinic/apyrimidinic (AP) endonuclease APE1 catalyses the hydrolysis of phosphodiester bonds on the 5′ side of an AP-site (in the base excision repair pathway) and of some damaged nucleotides (in the nucleotide incision repair pathway). The range of substrate specificity includes structurally...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuznetsova, Alexandra A, Matveeva, Anna G, Milov, Alexander D, Vorobjev, Yuri N, Dzuba, Sergei A, Fedorova, Olga S, Kuznetsov, Nikita A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265485/
https://www.ncbi.nlm.nih.gov/pubmed/30329131
http://dx.doi.org/10.1093/nar/gky912