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Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein

Improper maintenance of the mitochondrial genome progressively disrupts cellular respiration and causes severe metabolic disorders commonly termed mitochondrial diseases. Mitochondrial single-stranded DNA binding protein (mtSSB) is an essential component of the mtDNA replication machinery. We utiliz...

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Detalles Bibliográficos
Autores principales:	Kaur, Parminder, Longley, Matthew J, Pan, Hai, Wang, Hong, Copeland, William C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265486/ https://www.ncbi.nlm.nih.gov/pubmed/30256971 http://dx.doi.org/10.1093/nar/gky875

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