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Brain SIRT1 Mediates Metabolic Homeostasis and Neuroprotection
Sirtuins are evolutionarily conserved proteins that use nicotinamide adenine dinucleotide (NAD(+)) as a co-substrate in their enzymatic reactions. There are seven proteins (SIRT1-7) in the human sirtuin family, among which SIRT1 is the most conserved and characterized. SIRT1 in the brain, in particu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265504/ https://www.ncbi.nlm.nih.gov/pubmed/30532738 http://dx.doi.org/10.3389/fendo.2018.00702 |