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Brain SIRT1 Mediates Metabolic Homeostasis and Neuroprotection

Sirtuins are evolutionarily conserved proteins that use nicotinamide adenine dinucleotide (NAD(+)) as a co-substrate in their enzymatic reactions. There are seven proteins (SIRT1-7) in the human sirtuin family, among which SIRT1 is the most conserved and characterized. SIRT1 in the brain, in particu...

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Detalles Bibliográficos
Autores principales:	Xu, Jing, Jackson, Charlie W., Khoury, Nathalie, Escobar, Iris, Perez-Pinzon, Miguel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265504/ https://www.ncbi.nlm.nih.gov/pubmed/30532738 http://dx.doi.org/10.3389/fendo.2018.00702

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