Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin

Novel polypseudorotaxanes (PPR) based on poly(N-isopropylacrylamide) (PNIPAAm) and acrylamide-γ-cyclodextrin (AγCD) are successfully synthesized. AγCD gives rise to sliding crosslinking systems and influences the thermoresponsive and swelling behavior of PNIPAAm hydrogels. Namely, their lower critic...

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Autores principales: Malucelli, Giulio, Dore, Jvan, Sanna, Davide, Nuvoli, Daniele, Rassu, Mariella, Mariani, Alberto, Alzari, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265515/
https://www.ncbi.nlm.nih.gov/pubmed/30533412
http://dx.doi.org/10.3389/fchem.2018.00585
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author Malucelli, Giulio
Dore, Jvan
Sanna, Davide
Nuvoli, Daniele
Rassu, Mariella
Mariani, Alberto
Alzari, Valeria
author_facet Malucelli, Giulio
Dore, Jvan
Sanna, Davide
Nuvoli, Daniele
Rassu, Mariella
Mariani, Alberto
Alzari, Valeria
author_sort Malucelli, Giulio
collection PubMed
description Novel polypseudorotaxanes (PPR) based on poly(N-isopropylacrylamide) (PNIPAAm) and acrylamide-γ-cyclodextrin (AγCD) are successfully synthesized. AγCD gives rise to sliding crosslinking systems and influences the thermoresponsive and swelling behavior of PNIPAAm hydrogels. Namely, their lower critical solution temperature (LCST) can be tuned up to 38°C, thus making the resulting materials of great interest in biomedical applications. Also, AγCD influences the thermal and mechanical properties of hydrogels, by affecting the T(g) and E modulus values.
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spelling pubmed-62655152018-12-07 Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin Malucelli, Giulio Dore, Jvan Sanna, Davide Nuvoli, Daniele Rassu, Mariella Mariani, Alberto Alzari, Valeria Front Chem Chemistry Novel polypseudorotaxanes (PPR) based on poly(N-isopropylacrylamide) (PNIPAAm) and acrylamide-γ-cyclodextrin (AγCD) are successfully synthesized. AγCD gives rise to sliding crosslinking systems and influences the thermoresponsive and swelling behavior of PNIPAAm hydrogels. Namely, their lower critical solution temperature (LCST) can be tuned up to 38°C, thus making the resulting materials of great interest in biomedical applications. Also, AγCD influences the thermal and mechanical properties of hydrogels, by affecting the T(g) and E modulus values. Frontiers Media S.A. 2018-11-23 /pmc/articles/PMC6265515/ /pubmed/30533412 http://dx.doi.org/10.3389/fchem.2018.00585 Text en Copyright © 2018 Malucelli, Dore, Sanna, Nuvoli, Rassu, Mariani and Alzari. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Malucelli, Giulio
Dore, Jvan
Sanna, Davide
Nuvoli, Daniele
Rassu, Mariella
Mariani, Alberto
Alzari, Valeria
Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title_full Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title_fullStr Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title_full_unstemmed Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title_short Sliding Crosslinked Thermoresponsive Materials: Polypseudorotaxanes Made of Poly(N-Isopropylacrylamide) and Acrylamide-γ-Cyclodextrin
title_sort sliding crosslinked thermoresponsive materials: polypseudorotaxanes made of poly(n-isopropylacrylamide) and acrylamide-γ-cyclodextrin
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265515/
https://www.ncbi.nlm.nih.gov/pubmed/30533412
http://dx.doi.org/10.3389/fchem.2018.00585
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