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Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
Natural medicinal plants are multi-targeted in nature and their anti-cancer activities are also complex and varied, thus requiring a more systematic analysis of their modes of action. Since the activation of signal transducer and activator of transcription 3 (STAT3) is often deregulated in non-small...
Autores principales: | Lee, Jong Hyun, Kim, Chulwon, Lee, Seok-Geun, Sethi, Gautam, Ahn, Kwang Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265752/ https://www.ncbi.nlm.nih.gov/pubmed/30413072 http://dx.doi.org/10.3390/cancers10110427 |
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