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The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

Background: Osteosarcoma is the most frequent form of malignant pediatric bone tumor. Despite the current therapeutic arsenal, patient life-expectancy remains low if metastases are detected at the time of diagnosis, justifying research into better knowledge at all stages of osteosarcoma ontogenesis...

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Detalles Bibliográficos
Autores principales: Navet, Benjamin, Ando, Kosei, Vargas-Franco, Jorge William, Brion, Régis, Amiaud, Jérome, Mori, Kanji, Yagita, Hideo, Mueller, Christopher G., Verrecchia, Franck, Dumars, Clotilde, Heymann, Marie-Françoise, Heymann, Dominique, Lézot, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265790/
https://www.ncbi.nlm.nih.gov/pubmed/30355966
http://dx.doi.org/10.3390/cancers10110398