Cargando…

Cyclopeptide RA-V Inhibits Organ Enlargement and Tumorigenesis Induced by YAP Activation

The Hippo pathway restricts organ size during development and its inactivation plays a crucial role in cancer. Yes-associated protein (YAP) and its paralog transcriptional coactivator with PSD-95/Dlg/ZO-1 (PDZ)-binding motif (TAZ) are transcription co-activators and effectors of the Hippo pathway me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Xinyan, Song, Lihua, Sheng, Li, Gao, Anhui, Zhao, Yang, Han, Shixun, Zhang, Yuchao, Zhu, Chu, Zhao, Simeng, Wang, Zhe, Xu, Bohan, Li, Li, Li, Jia, Tan, Ninghua, Zhao, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265802/ https://www.ncbi.nlm.nih.gov/pubmed/30453531 http://dx.doi.org/10.3390/cancers10110449

Ejemplares similares

Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1
por: Wang, Zhe, et al.
Publicado: (2018)

Sequential Delivery of Cyclopeptide RA-V and Doxorubicin for Combination Therapy on Resistant Tumor and In Situ Monitoring of Cytochrome c Release
por: Chen, Huachao, et al.
Publicado: (2017)

Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells
por: Song, Lihua, et al.
Publicado: (2017)

TAK1 inhibition by natural cyclopeptide RA-V promotes apoptosis and inhibits protective autophagy in Kras-dependent non-small-cell lung carcinoma cells
por: Yang, Jianhong, et al.
Publicado: (2018)

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis
por: Shen, Shuying, et al.
Publicado: (2015)

Synthesis of Marine Cyclopeptide Galaxamide Analogues as Potential Anticancer Agents
por: Li, Daichun, et al.
Publicado: (2022)

Cyclopeptides from Amanita exitialis
por: Xue, Jing-Hua, et al.
Publicado: (2011)

Cancer Treatment by Caryophyllaceae-Type Cyclopeptides
por: Houshdar Tehrani, Mohammad Hassan, et al.
Publicado: (2021)

RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression
por: Guo, Di, et al.
Publicado: (2019)

Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation
por: Wang, Xiaoquan, et al.
Publicado: (2023)

Structural and bioactive studies of terpenes and cyclopeptides from the Genus Rubia
por: Xu, Kuo, et al.
Publicado: (2013)

Cyclopeptide Derivatives from the Sponge-Derived Fungus Acremonium persicinum F10
por: Li, Yingxin, et al.
Publicado: (2021)

Discovery and Characteristics of a Novel Antitumor Cyclopeptide Derived from Shark
por: Li, Fu, et al.
Publicado: (2023)

Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization
por: Oueis, Emilia, et al.
Publicado: (2016)

Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs
por: Herceg, Viktorija, et al.
Publicado: (2020)

Synthesis of novel cyclopeptides containing heterocyclic skeletons
por: Hamdan, Fatima, et al.
Publicado: (2018)

Insights on the Phytochemical Profile (Cyclopeptides) and Biological Activities of Calotropis procera Latex Organic Fractions
por: Jucá, Thiago Lustosa, et al.
Publicado: (2013)

Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N (9)-Methyl Group in the Conformation and Bioactivity
por: Wang, Zhe, et al.
Publicado: (2015)

Photoinduced Synthesis of Methylated Marine Cyclopeptide Galaxamide Analogs with Isoindolinone as Anticancer Agents
por: Xiao, Shimei, et al.
Publicado: (2022)

YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2017)

Natural Cyclopeptides as Anticancer Agents in the Last 20 Years
por: Zhang, Jia-Nan, et al.
Publicado: (2021)

Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis
por: Yang, Li, et al.
Publicado: (2021)

Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer
por: Wang, Tianshi, et al.
Publicado: (2023)

αvβ3 integrin-specific exosomes engineered with cyclopeptide for targeted delivery of triptolide against malignant melanoma
por: Gu, Yongwei, et al.
Publicado: (2022)

Correction: YAP promotes tumorigenesis and cisplatin resistance in neuroblastoma
por: Yang, Chao, et al.
Publicado: (2022)

Cyanobacterial Cyclopeptides as Lead Compounds to Novel Targeted Cancer Drugs
por: Sainis, Ioannis, et al.
Publicado: (2010)

Computational Discovery of Marine Molecules of the Cyclopeptide Family with Therapeutic Potential
por: Flores-Holguín, Norma, et al.
Publicado: (2023)

FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion
por: Li, Shuaifeng, et al.
Publicado: (2022)

Crosstalk Among YAP, LncRNA, and Tumor-Associated Macrophages in Tumorigenesis Development
por: Xu, Jing, et al.
Publicado: (2022)

The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
por: Zhang, Xiao, et al.
Publicado: (2017)

YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis
por: Li, Nianshuang, et al.
Publicado: (2023)

Silver-promoted solid-phase guanidinylation enables the first synthesis of arginine glycosylated Samoamide A cyclopeptide analogue
por: Liang, Bingxin, et al.
Publicado: (2023)

The emerging roles of TLR and cGAS signaling in tumorigenesis and progression of ovarian cancer
por: Zhang, Zhen, et al.
Publicado: (2022)

New 14-Membered Cyclopeptide Alkaloids from Zizyphus oxyphylla Edgew
por: Kaleem, Waqar Ahmad, et al.
Publicado: (2012)

Antiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids
por: Tuenter, Emmy, et al.
Publicado: (2017)

Jubanines F–J, cyclopeptide alkaloids from the roots of Ziziphus jujuba
por: Kang, Kyo Bin, et al.
Publicado: (2015)

Crossing of the Cystic Barriers of Toxoplasma gondii by the Fluorescent Coumarin Tetra-Cyclopeptide
por: Dard, Céline, et al.
Publicado: (2021)

Enzyme‐Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia
por: Molloy, Evelyn M., et al.
Publicado: (2021)

PKCι and YAP1 are crucial in promoting pancreatic tumorigenesis
por: Wang, Peipei, et al.
Publicado: (2018)

Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis
por: Zhang, Jinglin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_jsoo25fafqfbnnrmktuej0j9q9