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Transcription Factor Eb Is Required for Macropinocytosis-Mediated Growth Recovery of Nutrient-Deprived Kras-Mutant Cells
Macropinocytosis is a regulated form of endocytosis that mediates the nonselective uptake of nutrients to support growth under nutrient-deprived conditions. KRAS-mutant cancer cells upregulate macropinocytosis to import extracellular proteins, which subsequently undergo proteolytic degradation in th...
Autores principales: | Jeong, Seokmin, Byun, Jun-Kyu, Cho, Sung Jin, Chin, Jungwook, Lee, In-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265907/ https://www.ncbi.nlm.nih.gov/pubmed/30400219 http://dx.doi.org/10.3390/nu10111638 |
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