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Asymmetric Synthesis of the C15–C32 Fragment of Alotamide and Determination of the Relative Stereochemistry

Alotamide is a cyclic depsipetide isolated from a marine cyanobacterium and possesses a unique activation of calcium influx in murine cerebrocortical neurons (EC(50) 4.18 µM). Due to its limited source, the three stereocenters (C19, C28, and C30) in its polyketide fragment remain undetermined. In th...

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Detalles Bibliográficos
Autores principales:	Shi, Hao-yun, Xie, Yang, Hu, Pei, Guo, Zi-qiong, Lu, Yi-hong, Gao, Yu, Huang, Cheng-gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266257/ https://www.ncbi.nlm.nih.gov/pubmed/30380702 http://dx.doi.org/10.3390/md16110414

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