Cancerization of the Pancreatic Ducts: Demonstration of a Common and Under-recognized Process Using Immunolabeling of Paired Duct Lesions and Invasive Pancreatic Ductal Adenocarcinoma for p53 and Smad4 Expression

Invasive pancreatic ductal adenocarcinoma (PDAC) can infiltrate back into and spread along preexisting pancreatic ducts and ductules in a process known as cancerization of ducts (COD). Histologically COD can mimic high-grade pancreatic intraepithelial neoplasia (HG-PanIN). We reviewed pancreatic res...

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Detalles Bibliográficos
Autores principales: Hutchings, Danielle, Waters, Kevin M., Weiss, Matthew J., Wolfgang, Christopher L., Makary, Martin A., He, Jin, Cameron, John L., Wood, Laura D., Hruban, Ralph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health, Inc 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266304/
https://www.ncbi.nlm.nih.gov/pubmed/30212393
http://dx.doi.org/10.1097/PAS.0000000000001148

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