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Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer
Breast cancer (BC) is the most common type of cancer in women worldwide; it is a multifactorial genetic disease. Acetylation and deacetylation are major post-translational protein modifications that regulate gene expression and the activity of a myriad of oncoproteins. Aberrant deacetylase activity...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266715/ https://www.ncbi.nlm.nih.gov/pubmed/30380732 http://dx.doi.org/10.3390/cancers10110409 |