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Wound Healing Properties of Selected Natural Products

Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair proc...

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Autores principales: Ibrahim, Nurul ‘Izzah, Wong, Sok Kuan, Mohamed, Isa Naina, Mohamed, Norazlina, Chin, Kok-Yong, Ima-Nirwana, Soelaiman, Shuid, Ahmad Nazrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266783/
https://www.ncbi.nlm.nih.gov/pubmed/30366427
http://dx.doi.org/10.3390/ijerph15112360
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author Ibrahim, Nurul ‘Izzah
Wong, Sok Kuan
Mohamed, Isa Naina
Mohamed, Norazlina
Chin, Kok-Yong
Ima-Nirwana, Soelaiman
Shuid, Ahmad Nazrun
author_facet Ibrahim, Nurul ‘Izzah
Wong, Sok Kuan
Mohamed, Isa Naina
Mohamed, Norazlina
Chin, Kok-Yong
Ima-Nirwana, Soelaiman
Shuid, Ahmad Nazrun
author_sort Ibrahim, Nurul ‘Izzah
collection PubMed
description Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved.
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spelling pubmed-62667832018-12-15 Wound Healing Properties of Selected Natural Products Ibrahim, Nurul ‘Izzah Wong, Sok Kuan Mohamed, Isa Naina Mohamed, Norazlina Chin, Kok-Yong Ima-Nirwana, Soelaiman Shuid, Ahmad Nazrun Int J Environ Res Public Health Review Wound healing is a complex process of recovering the forms and functions of injured tissues. The process is tightly regulated by multiple growth factors and cytokines released at the wound site. Any alterations that disrupt the healing processes would worsen the tissue damage and prolong repair process. Various conditions may contribute to impaired wound healing, including infections, underlying diseases and medications. Numerous studies on the potential of natural products with anti-inflammatory, antioxidant, antibacterial and pro-collagen synthesis properties as wound healing agents have been performed. Their medicinal properties can be contributed by the content of bioactive phytochemical constituents such as alkaloids, essential oils, flavonoids, tannins, saponins, and phenolic compounds in the natural products. This review highlights the in vitro, in vivo and clinical studies on wound healing promotions by the selected natural products and the mechanisms involved. MDPI 2018-10-25 2018-11 /pmc/articles/PMC6266783/ /pubmed/30366427 http://dx.doi.org/10.3390/ijerph15112360 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ibrahim, Nurul ‘Izzah
Wong, Sok Kuan
Mohamed, Isa Naina
Mohamed, Norazlina
Chin, Kok-Yong
Ima-Nirwana, Soelaiman
Shuid, Ahmad Nazrun
Wound Healing Properties of Selected Natural Products
title Wound Healing Properties of Selected Natural Products
title_full Wound Healing Properties of Selected Natural Products
title_fullStr Wound Healing Properties of Selected Natural Products
title_full_unstemmed Wound Healing Properties of Selected Natural Products
title_short Wound Healing Properties of Selected Natural Products
title_sort wound healing properties of selected natural products
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266783/
https://www.ncbi.nlm.nih.gov/pubmed/30366427
http://dx.doi.org/10.3390/ijerph15112360
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