Silvestrol Inhibits Chikungunya Virus Replication

Silvestrol, a natural compound that is isolated from plants of the genus Aglaia, is a specific inhibitor of the RNA helicase eIF4A, which unwinds RNA secondary structures in 5′-untranslated regions (UTRs) of mRNAs and allows translation. Silvestrol has a broad antiviral activity against multiple RNA...

Descripción completa

Detalles Bibliográficos
Autores principales: Henss, Lisa, Scholz, Tatjana, Grünweller, Arnold, Schnierle, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266838/
https://www.ncbi.nlm.nih.gov/pubmed/30380742
http://dx.doi.org/10.3390/v10110592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266838/
https://www.ncbi.nlm.nih.gov/pubmed/30380742
http://dx.doi.org/10.3390/v10110592

Ejemplares similares