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Silvestrol Inhibits Chikungunya Virus Replication

Silvestrol, a natural compound that is isolated from plants of the genus Aglaia, is a specific inhibitor of the RNA helicase eIF4A, which unwinds RNA secondary structures in 5′-untranslated regions (UTRs) of mRNAs and allows translation. Silvestrol has a broad antiviral activity against multiple RNA...

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Detalles Bibliográficos
Autores principales:	Henss, Lisa, Scholz, Tatjana, Grünweller, Arnold, Schnierle, Barbara S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266838/ https://www.ncbi.nlm.nih.gov/pubmed/30380742 http://dx.doi.org/10.3390/v10110592

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