Cargando…
Genome Instability Induced by Low Levels of Replicative DNA Polymerases in Yeast
Most cells of solid tumors have very high levels of genome instability of several different types, including deletions, duplications, translocations, and aneuploidy. Much of this instability appears induced by DNA replication stress. As a model for understanding this type of instability, we have exa...
Autores principales: | Zheng, Dao-Qiong, Petes, Thomas D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267110/ https://www.ncbi.nlm.nih.gov/pubmed/30405078 http://dx.doi.org/10.3390/genes9110539 |
Ejemplares similares
-
Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases
por: Sui, Yang, et al.
Publicado: (2020) -
Global genomic instability caused by reduced expression of DNA polymerase ε in yeast
por: Zhang, Ke, et al.
Publicado: (2022) -
Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast
por: Zhang, Ke, et al.
Publicado: (2019) -
Low Levels of DNA Polymerase Alpha Induce Mitotic and Meiotic Instability in the Ribosomal DNA Gene Cluster of Saccharomyces cerevisiae
por: Casper, Anne M., et al.
Publicado: (2008) -
Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides
por: Sui, Yang, et al.
Publicado: (2022)