Management of young women with early breast cancer

Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The pres...

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Detalles Bibliográficos
Autores principales: Poggio, Francesca, Lambertini, Matteo, Bighin, Claudia, Conte, Benedetta, Blondeaux, Eva, D'Alonzo, Alessia, Dellepiane, Chiara, Boccardo, Francesco, Del Mastro, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267460/
https://www.ncbi.nlm.nih.gov/pubmed/30559981
http://dx.doi.org/10.1136/esmoopen-2018-000458
Descripción
Sumario:Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.

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