Management of young women with early breast cancer

Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The pres...

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Autores principales: Poggio, Francesca, Lambertini, Matteo, Bighin, Claudia, Conte, Benedetta, Blondeaux, Eva, D'Alonzo, Alessia, Dellepiane, Chiara, Boccardo, Francesco, Del Mastro, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267460/
https://www.ncbi.nlm.nih.gov/pubmed/30559981
http://dx.doi.org/10.1136/esmoopen-2018-000458
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author Poggio, Francesca
Lambertini, Matteo
Bighin, Claudia
Conte, Benedetta
Blondeaux, Eva
D'Alonzo, Alessia
Dellepiane, Chiara
Boccardo, Francesco
Del Mastro, Lucia
author_facet Poggio, Francesca
Lambertini, Matteo
Bighin, Claudia
Conte, Benedetta
Blondeaux, Eva
D'Alonzo, Alessia
Dellepiane, Chiara
Boccardo, Francesco
Del Mastro, Lucia
author_sort Poggio, Francesca
collection PubMed
description Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.
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spelling pubmed-62674602018-12-17 Management of young women with early breast cancer Poggio, Francesca Lambertini, Matteo Bighin, Claudia Conte, Benedetta Blondeaux, Eva D'Alonzo, Alessia Dellepiane, Chiara Boccardo, Francesco Del Mastro, Lucia ESMO Open Review Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation. BMJ Publishing Group 2018-11-14 /pmc/articles/PMC6267460/ /pubmed/30559981 http://dx.doi.org/10.1136/esmoopen-2018-000458 Text en © Author (s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ on behalf of the European Society for Medical Oncology. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, any changes made are indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0
spellingShingle Review
Poggio, Francesca
Lambertini, Matteo
Bighin, Claudia
Conte, Benedetta
Blondeaux, Eva
D'Alonzo, Alessia
Dellepiane, Chiara
Boccardo, Francesco
Del Mastro, Lucia
Management of young women with early breast cancer
title Management of young women with early breast cancer
title_full Management of young women with early breast cancer
title_fullStr Management of young women with early breast cancer
title_full_unstemmed Management of young women with early breast cancer
title_short Management of young women with early breast cancer
title_sort management of young women with early breast cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267460/
https://www.ncbi.nlm.nih.gov/pubmed/30559981
http://dx.doi.org/10.1136/esmoopen-2018-000458
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