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Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects with Renal Impairment

BACKGROUND: Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been co-formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) as a tablet for oral administration. This trial (NCT02014259) investigated the pharmacokinetics, safety and tolerability of...

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Detalles Bibliográficos
Autores principales:	Granhall, Charlotte, Søndergaard, Flemming L., Thomsen, Mette, Anderson, Thomas W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2018
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267549/ https://www.ncbi.nlm.nih.gov/pubmed/29623579 http://dx.doi.org/10.1007/s40262-018-0649-2

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