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Staurosporine, an inhibitor of hormonally up-regulated neu-associated kinase

HUNK is a protein kinase that is implicated in HER2-positive (HER2+) breast cancer progression and resistance to HER2 inhibitors. Though prior studies suggest there is therapeutic potential for targeting HUNK in HER2+ breast cancer, pharmacological agents that target HUNK are yet to be identified. A...

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Detalles Bibliográficos
Autores principales: Zambrano, Joelle N., Williams, Christina J., Williams, Carly Bess, Hedgepeth, Lonzie, Burger, Pieter, Dilday, Tinslee, Eblen, Scott T., Armeson, Kent, Hill, Elizabeth G., Yeh, Elizabeth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267597/
https://www.ncbi.nlm.nih.gov/pubmed/30542510
http://dx.doi.org/10.18632/oncotarget.26311