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Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer
Objective Our objective was to determine whether a delay in adjuvant radiotherapy is related to a decrease in relapse-free survival and disease-specific survival of women with operable breast cancer. Methods Data on 1000 patients diagnosed with breast cancer were recorded. The cohort was divided int...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267615/ https://www.ncbi.nlm.nih.gov/pubmed/30510860 http://dx.doi.org/10.7759/cureus.3071 |
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author | Flores-Balcázar, Christian H Flores-Luna, Lourdes Villarreal-Garza, Cynthia Mota-García, Aida Bargalló-Rocha, Enrique |
author_facet | Flores-Balcázar, Christian H Flores-Luna, Lourdes Villarreal-Garza, Cynthia Mota-García, Aida Bargalló-Rocha, Enrique |
author_sort | Flores-Balcázar, Christian H |
collection | PubMed |
description | Objective Our objective was to determine whether a delay in adjuvant radiotherapy is related to a decrease in relapse-free survival and disease-specific survival of women with operable breast cancer. Methods Data on 1000 patients diagnosed with breast cancer were recorded. The cohort was divided into five groups according to the timing of radiotherapy: ≤30 days, 31 to 60 days, 61 to 90 days, 91 to 120 days, and >120 days. The relapse-free survival and disease-specific survival were also calculated in relation to the number of patients. Results This study found no statistical difference for delays in adjuvant radiotherapy in patients with early breast cancer, but we noted a statistical decrease in disease-specific survival in patients with locally advanced breast cancer receiving radiotherapy after a delay of at least 60 days. Conclusion Waiting times for radiotherapy should be as short as reasonably achievable, given the specific risk factors in the individual patient. |
format | Online Article Text |
id | pubmed-6267615 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-62676152018-12-03 Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer Flores-Balcázar, Christian H Flores-Luna, Lourdes Villarreal-Garza, Cynthia Mota-García, Aida Bargalló-Rocha, Enrique Cureus Oncology Objective Our objective was to determine whether a delay in adjuvant radiotherapy is related to a decrease in relapse-free survival and disease-specific survival of women with operable breast cancer. Methods Data on 1000 patients diagnosed with breast cancer were recorded. The cohort was divided into five groups according to the timing of radiotherapy: ≤30 days, 31 to 60 days, 61 to 90 days, 91 to 120 days, and >120 days. The relapse-free survival and disease-specific survival were also calculated in relation to the number of patients. Results This study found no statistical difference for delays in adjuvant radiotherapy in patients with early breast cancer, but we noted a statistical decrease in disease-specific survival in patients with locally advanced breast cancer receiving radiotherapy after a delay of at least 60 days. Conclusion Waiting times for radiotherapy should be as short as reasonably achievable, given the specific risk factors in the individual patient. Cureus 2018-07-30 /pmc/articles/PMC6267615/ /pubmed/30510860 http://dx.doi.org/10.7759/cureus.3071 Text en Copyright © 2018, Flores-Balcázar et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Oncology Flores-Balcázar, Christian H Flores-Luna, Lourdes Villarreal-Garza, Cynthia Mota-García, Aida Bargalló-Rocha, Enrique Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title | Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title_full | Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title_fullStr | Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title_full_unstemmed | Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title_short | Impact of Delayed Adjuvant Radiotherapy in the Survival of Women with Breast Cancer |
title_sort | impact of delayed adjuvant radiotherapy in the survival of women with breast cancer |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267615/ https://www.ncbi.nlm.nih.gov/pubmed/30510860 http://dx.doi.org/10.7759/cureus.3071 |
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