Immune thrombocytopenia: improving quality of life and patient outcomes

Immune thrombocytopenia (ITP) is an immune-mediated disorder characterized by a reduced platelet count and patients may develop bruising or mucosal bleeding. Since 2003, generic health-related quality of life (HRQoL) measures have been applied and ITP-specific measures developed, alongside trials of...

Descripción completa

Detalles Bibliográficos
Autores principales: Trotter, Patrick, Hill, Quentin A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267629/
https://www.ncbi.nlm.nih.gov/pubmed/30568522
http://dx.doi.org/10.2147/PROM.S140932
_version_ 1783376118798090240
author Trotter, Patrick
Hill, Quentin A
author_facet Trotter, Patrick
Hill, Quentin A
author_sort Trotter, Patrick
collection PubMed
description Immune thrombocytopenia (ITP) is an immune-mediated disorder characterized by a reduced platelet count and patients may develop bruising or mucosal bleeding. Since 2003, generic health-related quality of life (HRQoL) measures have been applied and ITP-specific measures developed, alongside trials of novel therapeutic agents. These have identified significant morbidity in patients with ITP, including fatigue, fear of bleeding and a negative impact on role, social and work activities. This review critically evaluates HRQoL data in adults and children with ITP. It also considers the impact of treatment and how patient-reported outcomes might be applied to care to optimize patients’ quality of life.
format Online
Article
Text
id pubmed-6267629
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-62676292018-12-19 Immune thrombocytopenia: improving quality of life and patient outcomes Trotter, Patrick Hill, Quentin A Patient Relat Outcome Meas Review Immune thrombocytopenia (ITP) is an immune-mediated disorder characterized by a reduced platelet count and patients may develop bruising or mucosal bleeding. Since 2003, generic health-related quality of life (HRQoL) measures have been applied and ITP-specific measures developed, alongside trials of novel therapeutic agents. These have identified significant morbidity in patients with ITP, including fatigue, fear of bleeding and a negative impact on role, social and work activities. This review critically evaluates HRQoL data in adults and children with ITP. It also considers the impact of treatment and how patient-reported outcomes might be applied to care to optimize patients’ quality of life. Dove Medical Press 2018-11-27 /pmc/articles/PMC6267629/ /pubmed/30568522 http://dx.doi.org/10.2147/PROM.S140932 Text en © 2018 Trotter and Hill. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Trotter, Patrick
Hill, Quentin A
Immune thrombocytopenia: improving quality of life and patient outcomes
title Immune thrombocytopenia: improving quality of life and patient outcomes
title_full Immune thrombocytopenia: improving quality of life and patient outcomes
title_fullStr Immune thrombocytopenia: improving quality of life and patient outcomes
title_full_unstemmed Immune thrombocytopenia: improving quality of life and patient outcomes
title_short Immune thrombocytopenia: improving quality of life and patient outcomes
title_sort immune thrombocytopenia: improving quality of life and patient outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267629/
https://www.ncbi.nlm.nih.gov/pubmed/30568522
http://dx.doi.org/10.2147/PROM.S140932
work_keys_str_mv AT trotterpatrick immunethrombocytopeniaimprovingqualityoflifeandpatientoutcomes
AT hillquentina immunethrombocytopeniaimprovingqualityoflifeandpatientoutcomes

Ejemplares similares