Cargando…

Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol

BACKGROUND: Replicative senescence of human diploid fibroblasts (HDFs) has been used as a model to study mechanisms of cellular aging. Gamma-tocotrienol (γT3) is one of the members of vitamin E family which has been shown to increase proliferation of senescent HDFs. However, the modulation of protei...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tan, Jen-Kit, Jaafar, Faizul, Makpol, Suzana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267793/ https://www.ncbi.nlm.nih.gov/pubmed/30497457 http://dx.doi.org/10.1186/s12906-018-2383-6

Ejemplares similares

Cellular Uptake and Bioavailability of Tocotrienol-Rich Fraction in SIRT1-Inhibited Human Diploid Fibroblasts
por: Jaafar, Faizul, et al.
Publicado: (2018)

Gamma-Tocotrienol Modulated Gene Expression in Senescent Human Diploid Fibroblasts as Revealed by Microarray Analysis
por: Makpol, Suzana, et al.
Publicado: (2013)

Gamma-tocotrienol modulation of senescence-associated gene expression prevents cellular aging in human diploid fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2012)

Tocotrienol-Rich Fraction Prevents Cell Cycle Arrest and Elongates Telomere Length in Senescent Human Diploid Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2011)

Piper betle L. Modulates Senescence-Associated Genes Expression in Replicative Senescent Human Diploid Fibroblasts
por: Durani, Lina Wati, et al.
Publicado: (2017)

Modulation of Cell Cycle Profile by Chlorella vulgaris Prevents Replicative Senescence of Human Diploid Fibroblasts
por: Saberbaghi, Tayyebeh, et al.
Publicado: (2013)

Comparative Effects of Biodynes, Tocotrienol-Rich Fraction, and Tocopherol in Enhancing Collagen Synthesis and Inhibiting Collagen Degradation in Stress-Induced Premature Senescence Model of Human Diploid Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2013)

Targeting myomiRs by tocotrienol-rich fraction to promote myoblast differentiation
por: Razak, Azraul Mumtazah, et al.
Publicado: (2018)

Gelam honey attenuated radiation-induced cell death in human diploid fibroblasts by promoting cell cycle progression and inhibiting apoptosis
por: Tengku Ahmad, Tengku Ahbrizal Farizal, et al.
Publicado: (2014)

Comparative effect of Piper betle, Chlorella vulgaris and tocotrienol-rich fraction on antioxidant enzymes activity in cellular ageing of human diploid fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2013)

Modulation of Ki67 and myogenic regulatory factor expression by tocotrienol-rich fraction ameliorates myogenic program of senescent human myoblasts
por: Tan, Chun Min, et al.
Publicado: (2019)

Inhibition of Mitochondrial Cytochrome c Release and Suppression of Caspases by Gamma-Tocotrienol Prevent Apoptosis and Delay Aging in Stress-Induced Premature Senescence of Skin Fibroblasts
por: Makpol, Suzana, et al.
Publicado: (2012)

Elucidating the Pharmacological Properties of Zingiber officinale Roscoe (Ginger) on Muscle Ageing by Untargeted Metabolomic Profiling of Human Myoblasts
por: Mohd Sahardi, Nur Fatin Nabilah, et al.
Publicado: (2023)

Gelam Honey Protects against Gamma-Irradiation Damage to Antioxidant Enzymes in Human Diploid Fibroblasts
por: Ahmad, Tengku Ahbrizal Farizal Tengku, et al.
Publicado: (2013)

Untargeted muscle tissue metabolites profiling in young, adult, and old rats supplemented with tocotrienol-rich fraction
por: Saud Gany, Siti Liyana, et al.
Publicado: (2022)

Modulation of collagen synthesis and its gene expression in human skin fibroblasts by tocotrienol-rich fraction
por: Makpol, Suzana, et al.
Publicado: (2011)

Expression of Senescence-Associated microRNAs and Target Genes in Cellular Aging and Modulation by Tocotrienol-Rich Fraction
por: Gwee Sian Khee, Sharon, et al.
Publicado: (2014)

Zingiber Officinale Roscoe Prevents Cellular Senescence of Myoblasts in Culture and Promotes Muscle Regeneration
por: Mohd Sahardi, Nur Fatin Nabilah, et al.
Publicado: (2020)

Effect of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts
por: Zainuddin, Azalina, et al.
Publicado: (2010)

Tocotrienol-Rich Fraction Ameliorates Antioxidant Defense Mechanisms and Improves Replicative Senescence-Associated Oxidative Stress in Human Myoblasts
por: Khor, Shy Cian, et al.
Publicado: (2017)

The Tocotrienol-Rich Fraction Is Superior to Tocopherol in Promoting Myogenic Differentiation in the Prevention of Replicative Senescence of Myoblasts
por: Khor, Shy Cian, et al.
Publicado: (2016)

γ-Tocotrienol prevents oxidative stress-induced telomere shortening in human fibroblasts derived from different aged individuals
por: Makpol, Suzana, et al.
Publicado: (2010)

Methionine restriction slows down senescence in human diploid fibroblasts
por: Kozieł, Rafał, et al.
Publicado: (2014)

MicroRNA profiling in human diploid fibroblasts uncovers miR-519 role in replicative senescence
por: Marasa, Bernard S., et al.
Publicado: (2010)

Effects of tocotrienol on aging skin: A systematic review
por: Ghazali, Nur Izyani, et al.
Publicado: (2022)

Transcriptomic Analysis of the Anticancer Effects of Annatto Tocotrienol, Delta-Tocotrienol and Gamma-Tocotrienol on Chondrosarcoma Cells
por: Pang, Kok-Lun, et al.
Publicado: (2022)

Modulation of Proteome Profile in AβPP/PS1 Mice Hippocampus, Medial Prefrontal Cortex, and Striatum by Palm Oil Derived Tocotrienol-Rich Fraction
por: Hamezah, Hamizah Shahirah, et al.
Publicado: (2019)

Comparative Effects of Alpha- and Gamma-Tocopherol on Mitochondrial Functions in Alzheimer’s Disease In Vitro Model
por: Pahrudin Arrozi, Aslina, et al.
Publicado: (2020)

Persistent Amplification of DNA Damage Signal Involved in Replicative Senescence of Normal Human Diploid Fibroblasts
por: Suzuki, Masatoshi, et al.
Publicado: (2012)

DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts
por: Li, Bing Si, et al.
Publicado: (2021)

γ-Tocotrienol and 6-Gingerol in Combination Synergistically Induce Cytotoxicity and Apoptosis in HT-29 and SW837 Human Colorectal Cancer Cells
por: Md Yusof, Khairunnisa’, et al.
Publicado: (2015)

Tocotrienol-Rich Fraction, [6]-Gingerol and Epigallocatechin Gallate Inhibit Proliferation and Induce Apoptosis of Glioma Cancer Cells
por: Rahman, Amirah Abdul, et al.
Publicado: (2014)

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts
por: Greussing, Ruth, et al.
Publicado: (2013)

Gamma-tocotrienol, a radiation countermeasure, reverses proteomic changes in serum following total-body gamma irradiation in mice
por: Rosen, Elliot, et al.
Publicado: (2022)

CHOLESTEROL REQUIREMENT OF PRIMARY DIPLOID HUMAN FIBROBLASTS
por: Holmes, Richard, et al.
Publicado: (1969)

Sp1 Is Essential for p16(INK4a) Expression in Human Diploid Fibroblasts during Senescence
por: Wu, Junfeng, et al.
Publicado: (2007)

Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study
por: Chin, Siok-Fong, et al.
Publicado: (2011)

Progenitors Mobilized by Gamma-Tocotrienol as an Effective Radiation Countermeasure
por: Singh, Vijay K., et al.
Publicado: (2014)

Regulation of Obesity and Metabolic Complications by Gamma and Delta Tocotrienols
por: Zhao, Lu, et al.
Publicado: (2016)

A new formulation of Gamma Delta Tocotrienol has superior bioavailability compared to existing Tocotrienol-Rich Fraction in healthy human subjects
por: Meganathan, Puvaneswari, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3fsb081qmcoakvsl80vr9ubd66