Dyskinesia and brain-derived neurotrophic factor levels after long-term levodopa and nicotinic receptor agonist treatments in female mice with near-total unilateral dopaminergic denervation

BACKGROUND: The treatment of Parkinson’s disease is often complicated by levodopa-induced dyskinesia (LID). Nicotinic acetylcholine receptor agonists can alleviate LID in animal models but may be less effective in conditions of severe dopaminergic denervation. While the mechanisms of LID remain inco...

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Detalles Bibliográficos
Autores principales: Leino, Sakari, Kohtala, Samuel, Rantamäki, Tomi, Koski, Sini K., Rannanpää, Saara, Salminen, Outi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267795/
https://www.ncbi.nlm.nih.gov/pubmed/30497382
http://dx.doi.org/10.1186/s12868-018-0478-0

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