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Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes

BACKGROUND: Plants of Allium spp., including garlic (A. sativum) and onions (A. cepa), are known to be oxidatively toxic to canine erythrocytes resulting in Heinz body hemolytic anemia in dogs. In humans, these plants have been used as medicinal agents for multiple diseases since ancient times. Espe...

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Detalles Bibliográficos
Autores principales:	Yamato, Osamu, Tsuneyoshi, Tadamitsu, Ushijima, Mitsuyasu, Jikihara, Hiroshi, Yabuki, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267818/ https://www.ncbi.nlm.nih.gov/pubmed/30497454 http://dx.doi.org/10.1186/s12917-018-1699-2

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