Protein targets of thiazolidinone derivatives in Toxoplasma gondii and insights into their binding to ROP18

BACKGROUND: Thiazolidinone derivatives show inhibitory activity (IC(50)) against the Toxoplasma gondii parasite, as well as high selectivity with high therapeutic index. To disclose the target proteins of the thiazolidinone core in this parasite, we explored in silico the active sites of different T...

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Detalles Bibliográficos
Autores principales: Molina, Diego, Cossio-Pérez, Rodrigo, Rocha-Roa, Cristian, Pedraza, Lina, Cortes, Edwar, Hernández, Alejandro, Gómez-Marín, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267824/
https://www.ncbi.nlm.nih.gov/pubmed/30497375
http://dx.doi.org/10.1186/s12864-018-5223-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267824/
https://www.ncbi.nlm.nih.gov/pubmed/30497375
http://dx.doi.org/10.1186/s12864-018-5223-7

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