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Sample size calculation in multi-centre clinical trials
BACKGROUND: Multi-centre randomized controlled clinical trials play an important role in modern evidence-based medicine. Advantages of collecting data from more than one site are numerous, including accelerated recruitment and increased generalisability of results. Mixed models can be applied to acc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267841/ https://www.ncbi.nlm.nih.gov/pubmed/30497390 http://dx.doi.org/10.1186/s12874-018-0602-y |