Overexpression of miR-1 in the heart attenuates hippocampal synaptic vesicle exocytosis by the posttranscriptional regulation of SNAP-25 through the transportation of exosomes

BACKGROUND: The link between cardiac diseases and cognitive deterioration has been accepted from the concept of “cardiogenic dementia”, which was proposed in the late 1970s. However, the molecular mechanism is unclarified. METHODS: The two animal models used in this study were cardiac-specific overe...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Ming-Jing, Yan, Mei-Ling, Wang, Qin, Mao, Meng, Su, Dan, Sun, Lin-Lin, Li, Ke-Xin, Qu, Yang, Sun, Qiang, Zhang, Xin-Yu, Huang, Si-Yu, Ma, Ji-Chao, Ban, Tao, Ai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267908/
https://www.ncbi.nlm.nih.gov/pubmed/30497498
http://dx.doi.org/10.1186/s12964-018-0303-5

Ejemplares similares

Ejemplares similares