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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus

Recent genome-wide association studies (GWAS) have identified multiple new loci which appear to alter coronary artery disease (CAD) risk via arterial wall-specific mechanisms. One of the annotated genes encodes LMOD1 (Leiomodin 1), a member of the actin filament nucleator family that is highly enric...

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Detalles Bibliográficos
Autores principales:	Nanda, Vivek, Wang, Ting, Pjanic, Milos, Liu, Boxiang, Nguyen, Trieu, Matic, Ljubica Perisic, Hedin, Ulf, Koplev, Simon, Ma, Lijiang, Franzén, Oscar, Ruusalepp, Arno, Schadt, Eric E., Björkegren, Johan L. M., Montgomery, Stephen B., Snyder, Michael P., Quertermous, Thomas, Leeper, Nicholas J., Miller, Clint L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268002/ https://www.ncbi.nlm.nih.gov/pubmed/30444878 http://dx.doi.org/10.1371/journal.pgen.1007755

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