Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats

Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Resu...

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Detalles Bibliográficos
Autores principales: Zhu, Haiming, Ding, Liang, Xiao, Haijun, Ni, Weifeng, Xue, Feng, He, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268013/
https://www.ncbi.nlm.nih.gov/pubmed/22759913
http://dx.doi.org/10.3390/molecules17078001
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author Zhu, Haiming
Ding, Liang
Xiao, Haijun
Ni, Weifeng
Xue, Feng
He, Zhiming
author_facet Zhu, Haiming
Ding, Liang
Xiao, Haijun
Ni, Weifeng
Xue, Feng
He, Zhiming
author_sort Zhu, Haiming
collection PubMed
description Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats.
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spelling pubmed-62680132018-12-12 Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats Zhu, Haiming Ding, Liang Xiao, Haijun Ni, Weifeng Xue, Feng He, Zhiming Molecules Article Many commonly consumed foods, herbs and spices contain a complex array of naturally occurring bioactive molecules called phytochemicals, which may confer health benefits. In this study, the impact of LiuWei Zhuanggu Granules (LWZGG) on mineral metabolism in osteopenia development was evaluated. Results showed that serum estrogen, bone gla protein (BGP), and calcitonin (CT) levels, bone Ca, Zn and Cu levels, femur, lumbar vertebrae and trabecular bone density, tibia maximum stress and maximum bending strength were increased, and serum parathyroid hormone (PTH), serum and urine Ca, Zn and Cu levels were decreased in rat bone. It can be concluded that LWZGG is useful to improve bone quality in ovariectomized (OVX) rats. MDPI 2012-07-03 /pmc/articles/PMC6268013/ /pubmed/22759913 http://dx.doi.org/10.3390/molecules17078001 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Zhu, Haiming
Ding, Liang
Xiao, Haijun
Ni, Weifeng
Xue, Feng
He, Zhiming
Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title_full Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title_fullStr Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title_full_unstemmed Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title_short Pharmacological Evaluation of LiuWei Zhuanggu Granules in Rats
title_sort pharmacological evaluation of liuwei zhuanggu granules in rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268013/
https://www.ncbi.nlm.nih.gov/pubmed/22759913
http://dx.doi.org/10.3390/molecules17078001
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AT xiaohaijun pharmacologicalevaluationofliuweizhuanggugranulesinrats
AT niweifeng pharmacologicalevaluationofliuweizhuanggugranulesinrats
AT xuefeng pharmacologicalevaluationofliuweizhuanggugranulesinrats
AT hezhiming pharmacologicalevaluationofliuweizhuanggugranulesinrats

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