Synthesis and Characterization of Cationic Glycidyl-Based Poly(aminoester)-Folic Acid Targeting Conjugates and Study on Gene Delivery

A new poly(aminoester) (EPAE-FA) containing folic acid and amino groups in the backbone and side chain was synthesized. EPAE-FA self-assembled readily with the plasmid DNA (pCMV-βgal) in HEPES buffer and was characterized by dynamic light scattering, zeta potential, fluorescence images, and XTT cell...

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Detalles Bibliográficos
Autores principales: Tsai, Pai Feng, Chang, Wei Yang, Hsiao, Yu Che, Li, Kuo Jung, Shau, Min Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268037/
https://www.ncbi.nlm.nih.gov/pubmed/22847144
http://dx.doi.org/10.3390/molecules17089056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268037/
https://www.ncbi.nlm.nih.gov/pubmed/22847144
http://dx.doi.org/10.3390/molecules17089056

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