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Investigation of the Biological Properties of (Hetero)Aromatic Thiosemicarbazones

Two series of thiosemicarbazone-based iron chelators (twenty-seven compounds) were designed and synthesized using a microwave-assisted approach. Quinoline and halogenated phenyl were selected as parent scaffolds on the basis of a similarity search. The lipophilicity of the synthesized compounds was...

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Detalles Bibliográficos
Autores principales: Serda, Maciej, Mrozek-Wilczkiewicz, Anna, Jampilek, Josef, Pesko, Matus, Kralova, Katarina, Vejsova, Marcela, Musiol, Robert, Ratuszna, Alicja, Polanski, Jaroslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268061/
https://www.ncbi.nlm.nih.gov/pubmed/23151918
http://dx.doi.org/10.3390/molecules171113483