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Investigation of Non-Enzymatic Glycosylation of Human Serum Albumin Using Ion Trap-Time of Flight Mass Spectrometry

Non-enzymatic glycosylation or glycation involves covalent attachment of reducing sugar residues to proteins without enzyme participation. Glycation of glucose to human serum albumin in vivo is related to diabetes and many other diseases. We present an approach using liquid chromatography coupled to...

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Detalles Bibliográficos
Autores principales: Bai, Xue, Wang, Zhangjie, Huang, Chengcai, Wang, Zhe, Chi, Lianli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268088/
https://www.ncbi.nlm.nih.gov/pubmed/22832880
http://dx.doi.org/10.3390/molecules17088782