The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside

Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of Hyptis verticillata.

Detalles Bibliográficos
Autores principales: Hamada, Toshiyuki, White, Yohann, Nakashima, Mitsuyoshi, Oiso, Yusuke, Fujita, Masaki J., Okamura, Hiroaki, Iwagawa, Tetsuo, Arima, Naomichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268098/
https://www.ncbi.nlm.nih.gov/pubmed/22902886
http://dx.doi.org/10.3390/molecules17089931
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author Hamada, Toshiyuki
White, Yohann
Nakashima, Mitsuyoshi
Oiso, Yusuke
Fujita, Masaki J.
Okamura, Hiroaki
Iwagawa, Tetsuo
Arima, Naomichi
author_facet Hamada, Toshiyuki
White, Yohann
Nakashima, Mitsuyoshi
Oiso, Yusuke
Fujita, Masaki J.
Okamura, Hiroaki
Iwagawa, Tetsuo
Arima, Naomichi
author_sort Hamada, Toshiyuki
collection PubMed
description Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of Hyptis verticillata.
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spelling pubmed-62680982018-12-12 The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside Hamada, Toshiyuki White, Yohann Nakashima, Mitsuyoshi Oiso, Yusuke Fujita, Masaki J. Okamura, Hiroaki Iwagawa, Tetsuo Arima, Naomichi Molecules Article Through bioassay-guided isolation, five compounds with growth inhibitory activity on S1T, an adult T-cell leukemia (ATL) cell line, were isolated from the crude methanol extract of the aerial parts of Hyptis verticillata. MDPI 2012-08-17 /pmc/articles/PMC6268098/ /pubmed/22902886 http://dx.doi.org/10.3390/molecules17089931 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hamada, Toshiyuki
White, Yohann
Nakashima, Mitsuyoshi
Oiso, Yusuke
Fujita, Masaki J.
Okamura, Hiroaki
Iwagawa, Tetsuo
Arima, Naomichi
The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title_full The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title_fullStr The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title_full_unstemmed The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title_short The Bioassay-Guided Isolation of Growth Inhibitors of Adult T-Cell Leukemia (ATL), from the Jamaican Plant Hyptis verticillata, and NMR Characterization of Hyptoside
title_sort bioassay-guided isolation of growth inhibitors of adult t-cell leukemia (atl), from the jamaican plant hyptis verticillata, and nmr characterization of hyptoside
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268098/
https://www.ncbi.nlm.nih.gov/pubmed/22902886
http://dx.doi.org/10.3390/molecules17089931
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