The Photodegradation of Quercetin: Relation to Oxidation

The photostability of quercetin in alcoholic solutions was studied. Both UVA and UVB light induced degradation of quercetin, yielding a single product 1 deriving from oxidation and addition of an alcohol molecule to the 2,3 double bond. The same mechanism operated when quercetin was dissolved in alk...

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Detalles Bibliográficos
Autores principales: Dall’Acqua, Stefano, Miolo, Giorgia, Innocenti, Gabbriella, Caffieri, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268119/
https://www.ncbi.nlm.nih.gov/pubmed/22836209
http://dx.doi.org/10.3390/molecules17088898
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author Dall’Acqua, Stefano
Miolo, Giorgia
Innocenti, Gabbriella
Caffieri, Sergio
author_facet Dall’Acqua, Stefano
Miolo, Giorgia
Innocenti, Gabbriella
Caffieri, Sergio
author_sort Dall’Acqua, Stefano
collection PubMed
description The photostability of quercetin in alcoholic solutions was studied. Both UVA and UVB light induced degradation of quercetin, yielding a single product 1 deriving from oxidation and addition of an alcohol molecule to the 2,3 double bond. The same mechanism operated when quercetin was dissolved in alkaline solutions, and again a product 2 due to oxidation and addition of water was characterized. Comparison with quercetin analogs confirmed that, despite the presence of five hydroxy groups in quercetin, those in positions 3, 3′, and 4′ are mainly involved in the antioxidant activity of the compound , as well as in its photolability.
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spelling pubmed-62681192018-12-12 The Photodegradation of Quercetin: Relation to Oxidation Dall’Acqua, Stefano Miolo, Giorgia Innocenti, Gabbriella Caffieri, Sergio Molecules Article The photostability of quercetin in alcoholic solutions was studied. Both UVA and UVB light induced degradation of quercetin, yielding a single product 1 deriving from oxidation and addition of an alcohol molecule to the 2,3 double bond. The same mechanism operated when quercetin was dissolved in alkaline solutions, and again a product 2 due to oxidation and addition of water was characterized. Comparison with quercetin analogs confirmed that, despite the presence of five hydroxy groups in quercetin, those in positions 3, 3′, and 4′ are mainly involved in the antioxidant activity of the compound , as well as in its photolability. MDPI 2012-07-26 /pmc/articles/PMC6268119/ /pubmed/22836209 http://dx.doi.org/10.3390/molecules17088898 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Dall’Acqua, Stefano
Miolo, Giorgia
Innocenti, Gabbriella
Caffieri, Sergio
The Photodegradation of Quercetin: Relation to Oxidation
title The Photodegradation of Quercetin: Relation to Oxidation
title_full The Photodegradation of Quercetin: Relation to Oxidation
title_fullStr The Photodegradation of Quercetin: Relation to Oxidation
title_full_unstemmed The Photodegradation of Quercetin: Relation to Oxidation
title_short The Photodegradation of Quercetin: Relation to Oxidation
title_sort photodegradation of quercetin: relation to oxidation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268119/
https://www.ncbi.nlm.nih.gov/pubmed/22836209
http://dx.doi.org/10.3390/molecules17088898
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