Cargando…

The Kabachnik–Fields Reaction: Mechanism and Synthetic Use

The Kabachnik–Fields (phospha-Mannich) reaction involving the condensation of primary or secondary amines, oxo compounds (aldehydes and ketones) and >P(O)H species, especially dialkyl phosphites, represents a good choice for the synthesis of α-aminophosphonates that are of significant importance...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keglevich, György, Bálint, Erika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268146/ https://www.ncbi.nlm.nih.gov/pubmed/23117425 http://dx.doi.org/10.3390/molecules171112821

Ejemplares similares

Microwave-Assisted Kabachnik–Fields Reaction with Amino Alcohols as the Amine Component
por: Tajti, Ádám, et al.
Publicado: (2019)

Synthesis of α-Aminophosphonates and Related Derivatives; The Last Decade of the Kabachnik–Fields Reaction
por: Varga, Petra R., et al.
Publicado: (2021)

Cytotoxic Activity of α-Aminophosphonic Derivatives Coming from the Tandem Kabachnik–Fields Reaction and Acylation
por: Varga, Petra R., et al.
Publicado: (2023)

Zirconium-catalyzed asymmetric Kabachnik–Fields reactions of aromatic and aliphatic aldehydes
por: Dai, Yijing, et al.
Publicado: (2021)

Application of the Microwave Technique in Continuous Flow Processing of Organophosphorus Chemical Reactions
por: Bálint, Erika, et al.
Publicado: (2019)

The synthesis of HMF-based α-amino phosphonates via one-pot Kabachnik–Fields reaction
por: Fan, Weigang, et al.
Publicado: (2018)

Study on the Microwave-Assisted Batch and Continuous Flow Synthesis of N-Alkyl-Isoindolin-1-One-3-Phosphonates by a Special Kabachnik–Fields Condensation
por: Tajti, Ádám, et al.
Publicado: (2020)

Nanostructured N doped TiO(2) efficient stable catalyst for Kabachnik–Fields reaction under microwave irradiation
por: Kunde, Sachin P., et al.
Publicado: (2020)

Relationship between Structure and Antibacterial Activity of α-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik−Fields Reaction
por: Koszelewski, Dominik, et al.
Publicado: (2022)

Surface Engineering of Fluoropolymer Films via the Attachment of Crown Ether Derivatives Based on the Combination of Radiation-Induced Graft Polymerization and the Kabachnik–Fields Reaction
por: Omichi, Masaaki, et al.
Publicado: (2019)

Synthesis and Reactions of α-Hydroxyphosphonates
por: Rádai, Zita, et al.
Publicado: (2018)

Focusing on the Catalysts of the Pd- and Ni-Catalyzed Hirao Reactions
por: Keglevich, György, et al.
Publicado: (2020)

Continuous Flow Alcoholysis of Dialkyl H-Phosphonates with Aliphatic Alcohols
por: Bálint, Erika, et al.
Publicado: (2018)

Microwave-assisted synthesis of N,N-bis(phosphinoylmethyl)amines and N,N,N-tris(phosphinoylmethyl)amines bearing different substituents on the phosphorus atoms
por: Bálint, Erika, et al.
Publicado: (2019)

The synthesis of α-aryl-α-aminophosphonates and α-aryl-α-aminophosphine oxides by the microwave-assisted Pudovik reaction
por: Bálint, Erika, et al.
Publicado: (2017)

Microwave-assisted synthesis of (aminomethylene)bisphosphine oxides and (aminomethylene)bisphosphonates by a three-component condensation
por: Bálint, Erika, et al.
Publicado: (2016)

New Developments on the Hirao Reactions, Especially from “Green” Point of View
por: Henyecz, Réka, et al.
Publicado: (2019)

Tetraalkyl Hydroxymethylene-bisphosphonate and Dialkyl 1-Diphenylphosphinoyl-1-hydroxy-ethylphosphonate Derivatives by the Pudovik Reaction and Their Rearranged Products
por: Szalai, Zsuzsanna, et al.
Publicado: (2021)

Microwaves as “Co-Catalysts” or as Substitute for Catalysts in Organophosphorus Chemistry
por: Keglevich, György
Publicado: (2021)

Experimental and Theoretical Study on the “2,2′-Bipiridyl-Ni-Catalyzed” Hirao Reaction of >P(O)H Reagents and Halobenzenes: A Ni(0) → Ni(II) or a Ni(II) → Ni(IV) Mechanism?
por: Keglevich, György, et al.
Publicado: (2020)

The Palladium Acetate‐Catalyzed Microwave‐Assisted Hirao Reaction without an Added Phosphorus Ligand as a “Green” Protocol: A Quantum Chemical Study on the Mechanism
por: Keglevich, György, et al.
Publicado: (2017)

The Hydrolysis of Phosphinates and Phosphonates: A Review
por: Harsági, Nikoletta, et al.
Publicado: (2021)

The Last Decade of Optically Active α-Aminophosphonates
por: Varga, Petra R., et al.
Publicado: (2023)

Editorial to the Organophosphorus Chemistry Special Issue of Molecules (2012–2014)
por: Keglevich, György
Publicado: (2014)

Organophosphorus chemistry: from model to application
por: Keglevich, György
Publicado: (2023)

Organophosphorus Chemistry 2021
por: Keglevich, György
Publicado: (2023)

Modifications on the Basic Skeletons of Vinblastine and Vincristine
por: Keglevich, Péter, et al.
Publicado: (2012)

Interface Reactions and Synthetic Reaction of Composite Systems
por: Park, Joon Sik, et al.
Publicado: (2010)

Microwave-assisted simple synthesis of 2-anilinopyrimidines by the reaction of 2-chloro-4,6-dimethylpyrimidine with aniline derivatives
por: Campestre, Cristina, et al.
Publicado: (2020)

Synthesis of Hydroxymethylenebisphosphonic Acid Derivatives in Different Solvents
por: Nagy, Dávid Illés, et al.
Publicado: (2016)

Synthesis and Cytotoxic Activity of New Vindoline Derivatives Coupled to Natural and Synthetic Pharmacophores
por: Keglevich, András, et al.
Publicado: (2020)

Synthetic- and DFT modelling studies on regioselective modified Mannich reactions of hydroxy-KYNA derivatives
por: Lőrinczi, Bálint, et al.
Publicado: (2020)

Microwave-Assisted Palladium Acetate-Catalyzed C–P Cross-Coupling of Arylboronic Acids and >P(O)H Reagents in the Absence of the Usual Mono- and Bidentate P-Ligands: Mechanistic Insights
por: Huszár, Bianka, et al.
Publicado: (2023)

Selectivity in multiple multicomponent reactions: types and synthetic applications
por: Ghashghaei, Ouldouz, et al.
Publicado: (2019)

Synthetic Applications of Intramolecular Thiol-Ene “Click” Reactions
por: Scanlan, Eoin M., et al.
Publicado: (2014)

Synthetic Enzyme‐Catalyzed CO(2) Fixation Reactions
por: Aleku, Godwin A., et al.
Publicado: (2021)

A Study of the Bisphosphonic Derivatives from the Pudovik Reaction of Dialkyl α-Oxophosphonates and >P(O)H Reagents: X-ray Structure and Bioactivity
por: Szalai, Zsuzsanna, et al.
Publicado: (2023)

Continuous Flow Esterification of a H-Phosphinic Acid, and Transesterification of H-Phosphinates and H-Phosphonates under Microwave Conditions
por: Kiss, Nóra Zsuzsa, et al.
Publicado: (2020)

A Mechanistic Study on the Formation of Dronic Acids
por: Ábrányi-Balogh, Péter, et al.
Publicado: (2021)

Synthetic half-reactions
por: Yudin, Andrei K.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9stbrbt3go26chvrco848sad27